DESIGNING A SUSTAINABLE STRATEGY FOR MALARIA CONTROL?

Designing a sustainable strategy for malaria control?

Abstract Malaria in the 21st century is showing signs of declining over much of its distribution, including several countries in Africa where previously this was not thought to be feasible.Yet for the most part the strategies to attack the infection are similar to those of the 1950s.Three Multi-Tools major Journals have recently drawn attention to

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HIV-1 Uncoating and Nuclear Import Precede the Completion of Reverse Transcription in Cell Lines and in Primary Macrophages

An assembly of capsid proteins (CA) form the mature viral core enclosing the HIV-1 ribonucleoprotein complex.Discrepant findings have been reported regarding the cellular sites and the extent of core disassembly (uncoating) in infected cells.Here, we combined single-virus imaging and time-of-drug-addition assays to elucidate the kinetic relationshi

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